Sickle cell disease

Sickle cell disease

• About sickle cell disease
• ​Symptoms and diagnosis
• ​Treating sickle cell disease
• ​Living with sickle cell disease
• ​Causes of sickle cell disease
• ​Sickle cell disease carriers and screening

About sickle cell disease

Sickle cell disease is the name for a group of blood disorders. The most severe is sickle cell anaemia. These disorders are inherited, meaning they are passed on through your genes.

You can have a blood test at any time to find out if you carry the gene for sickle cell disease, or if you have sickle cell disease.

Sickle cell disease affects how your body produces red blood cells. Normal red blood cells are round – red blood cells affected by sickle cell disease harden and become sickle-shaped, like a crescent moon. This causes them to die too quickly and block blood vessels, leading to symptoms that are often painful.

People from particular ethnic backgrounds are more likely to have sickle cell disease or carry the gene. You are more likely to have sickle cell disease if you are from one of these ethnic backgrounds:

• African
• Asian
• Caribbean
• Eastern Mediterranean
• Middle Eastern

There are treatments to manage sickle cell disease, but no cure yet – it’s a lifelong condition.

Find out about symptoms and diagnosis

Find out about treating sickle cell disease

Find out about living with sickle cell disease

Find out about screening to see if you’re a sickle cell carrier